Sporotrichosis in Children: Case series and Narrative Review

AbstractPurpose of ReviewPediatric sporotrichosis has not been sufficiently studied; this review aims to evaluate the risk and prognostic factors related to the development of sporotrichosis associated to this age group. Also, we want to evaluate the causes of the increased number of cases of sporotrichosis in the pediatric population such as environmental changes in endemic areas, the biodiversity, and virulence among the pathogenic clade causing sporotrichosis in different areas of the globe, and especially the progression of the zoonotic transmission of infections caused bySporothrix brasiliensis infections, associated to zoonotic transmission in Brazil and other endemic sporotrichosis countries.Recent FindingsAfter evaluating a case series of 40 patients, we found that pediatric sporotrichosis in Mexico is mainly caused bySporothrix schenckii which prevails in rural areas and is mainly sapronotically transmitted. In Brazil, the longest and largest pediatric sporotrichosis outbreak is caused bySporothrix brasiliensis, etiologically related to sick cats, directly from lesions containing a high yeast cell burden. When affecting childrenS. schenckii andS. brasiliensis may cause distinct clinical manifestations especially in the onset of the disease and affected anatomical site. In Mexico, most of the patients are successfully treated with potassium iodide, whereas in Brazil, all patients respond to itraconazole.SummarySporothrix schenckii is the major etiologic agent in Mexic...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research