E-105 Analysis of clinical associations of serum SCFAs taken at the time of thrombectomy in AIS patients

ConclusionsThe evaluation of SCFAs in the serum at the time of stroke provides novel insight into the potential role of SCFAs during stroke in human patients. Age remains a significant factor to SCFA concentrations in stroke patients. The length of time following stroke also contributes to the levels of SCFAs. Previous studies have shown that increased levels of SCFAs is associated with decreased severity of stroke, however our data did not detect any such effect. This observation may be due to the acute time of the blood collection following stroke and analyzing serum instead of fecal samples. Furthermore, acquiring information about variations in diet and gut microbiota between patients may help explain inter-individual differences in baseline SCFA levels. The quantification of serum SCFAs prior to thrombectomy warrants additional analysis to determine their early role in the systemic response to stroke.Disclosures N. Henry: None. J. Frank: None. J. Fraser: None. A. Trout: None. A. Morris: None. J. Chen: None. A. Stowe: 1; C; American Heart Association, NIH Grants. 6; C; Cerelux, LLC. C. McLouth: None. K. Pennypacker: 6; C; Cerelux, LLC.
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: Electronic poster abstracts Source Type: research