Oxidative stress indices in ASD children in Sub-Sahara Africa

ConclusionReduction in Zn and Mg levels with a concurrent increase in Pb in children with ASD in this study may be the basis of inadequate TAC manifesting as increased MDA and reduced TPP levels. The attendant imbalance in oxidant/antioxidant ratio may result in abnormality in neuronal transduction leading to the abnormal cognitive and speech functions characteristic of ASD.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research