A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants

Condition:   Diarrhoea Interventions:   Drug: altSonflex Placebo;   Biological: altSonflex1-2-3 Dose C;   Biological: altSonflex1-2-3 Dose B;   Biological: altSonflex1-2-3 Dose A;   Biological: GSK's Meningococcal A, C, Y and W-135 conjugate vaccine;   Combination Product: GSK's Tetanus toxoid, reduced diphtheria toxoi d and acellular pertussis vaccine;   Combination Product: GSK's Poliomyelitis, diphtheria, tetanus and pertussis vaccine;   Combination Product: Sanofi Pasteur's Typhoid Vi polysaccharide vaccine;   Biological: Serum Institute of India's Measles and rubella vaccine Sponsor:   GlaxoSmithKline Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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AbstractCurrently, the world is witnessing the pandemic of COVID-19, a disease caused by the novel coronavirus SARS-CoV-2. Reported differences in clinical manifestations and outcomes in SARS-CoV-2 infection could be attributed to factors such as virus replication, infiltration of inflammatory cells, and altered cytokine production. Virus-induced aberrant and excessive cytokine production has been linked to the morbidity and mortality of several viral infections. Using a Luminex platform, we investigated plasma cytokine and chemokine levels of 27 analytes from hospitalized asymptomatic (n = 39) and mildly symptomatic (n = ...
Source: Archives of Virology - Category: Virology Source Type: research
WHO names variant found in Belgium and Israel OmicronWhite House adviser Fauci: no indication variant is in USBioNTech says vaccine can be tweaked in 100 days if neededJoe Biden ’s chief medical adviser, Anthony Fauci, said on Friday there was “no indication” the new “Omicron” coronavirus variant discovered in southern Africa had reached the US.Nonetheless, the the Biden administration said it would restrict travel from South Africa and seven other countries in southern Africa, starting on Monday.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Biden administration Coronavirus Infectious diseases World news Science US news US domestic policy US foreign policy Air transport South Africa Source Type: news
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