Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis

CONCLUSIONS: Our study highlights the critical function of miR-221/222, which inhibited Irf2 translation, in the anti-inflammatory effects of propofol, and provides a new perspective for the molecular mechanism of propofol-mediated neuroprotective effect.PMID:34423051 | PMC:PMC8373515 | DOI:10.1155/2021/3101146

Source: Journal of Immunology Research - August 23, 2021 Category: Allergy & Immunology Authors: Xi Xiao Yuanyuan Hou Wei Yu Sihua Qi Source Type: research