The association between cardiovascular risk factors and major cardiovascular diseases decreases with increasing frailty levels in geriatric outpatients

CONCLUSION: Frailty and CVRF are both associated with CVD, but the impact of CVRF decreases in the presence of frailty. When confirmed in longitudinal studies, randomized controlled trials or causal inference methods like Mendelian randomization should be applied to assess whether a shift from traditional CVRF to frailty would improve cardiovascular outcome in the oldest old.PMID:34265412 | DOI:10.1016/j.exger.2021.111475

Source: Experimental Gerontology - July 15, 2021 Category: Geriatrics Authors: Ivan Aprahamian Marina Petrella Everson C Robello H élder Jorge Andrade Gomes Nat ália A Lima Isabela C Fernandes Fernanda Rezende Dias da Silva Daniele Lima da Costa Andr éia Pain Mateus de Oliveira Reis Claudia K Suemoto Richard C Oude Voshaar Source Type: research