LncRNA CCAT1 sponges miR-218-5p to promote EMT, cellular migration and invasion of retinoblastoma by targeting MTF2

In conclusion, here we identified the lncRNA CCAT1/miR-218-5p/MTF2 axis in RB cell lines. Our investigations on the function of lncRNA CCAT1 hint a novel biomarker and therapeutic option to facilitate RB diagnosis and treatment.PMID:34265414 | DOI:10.1016/j.cellsig.2021.110088

Source: Cellular Signalling - July 15, 2021 Category: Cytology Authors: Xiangbo Meng Yixia Zhang Yongping Hu Jianguang Zhong Chunming Jiang Hongxu Zhang Source Type: research