Pulmonary function test abnormalities in children and adolescents with non-alcoholic fatty liver disease

Conclusion: PFT indices were impaired in children with NAFLD and this impairment was independently associated with insulin resistance and hs-CRP.What is Known:•Pulmonary function tests (PFTs) abnormalities are common in adults with nonalcoholic fatty liver disease (NAFLD).•Studies involving PFTs abnormalities in pediatric NAFLD are lacking.What is New:•It is the first study that assessed PFT in pediatric patients with NAFLD.•PFTs abnormalities are present in children with NAFLD.•Insulin resistance and high sensitive C reactive protein are independently associated with the decline of PFTs in children with NAFLD.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research