Comparison of the immunogenicity & amp; protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates

CONCLUSIONS: Our findings highlighted onset of quick immunogenicity and protective efficacy of mRNA-1273, followed by Ad26.CoV2.S, NVX-CoV2373, BNT162b2, RBD and BBV152 vaccine candidates in preclinical trials as compared to the others. NHP data also showed correlation with clinical trial data available for a few vaccines. Preclinical trials of COVID-19 vaccine candidates in NHPs yielded promising results, with some candidates faring better than others.PMID:33361645 | DOI:10.4103/ijmr.IJMR_4431_20
Source: The Indian Journal of Medical Research - Category: Biomedical Science Authors: Source Type: research