MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells

Conclusion:
The results indicate that miR-130b plays an oncogenic role in ESCC cells by repressing PTEN expression and Akt phosphorylation, which would be helpful in developing miRNA-based treatments for ESCC.

Source: BMC Cancer - January 31, 2015 Category: Cancer & Oncology Authors: Tingting YuRisheng CaoShuo LiMingen FuLihua RenWeixu ChenHong ZhuQiang ZhanRuihua Shi Source Type: research