Loss of Ribbon Synapses as an Early Stage of Age-Related Hearing Loss

In this study, we aimed to verify whether cochlear ribbon synapses are vulnerable to aging insult in C57BL/6J mice, a widespread model for ARHL. We explored the correlation between the number and function of ribbon synapses and the reduction of hearing function in the early stage of aging. We found that the loss of cochlear ribbon synapses is an initial pathological event in the early stage of aging, which causes hearing loss and may consequently induce loss or damage to other cochlear components, such as IHCs, and SGNs. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724364/
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs