Forthcoming Book: Replacing Aging

Replacing Aging is a forthcoming book on the treatment of aging as a medical condition. It is presented as putting forward a similar point of view to that found in Ending Aging by Aubrey de Grey and Michael Rae, meaning that the research and medical communities should place a relentless focus on damage and repair of damage. Aging is caused by an accumulation of molecular damage of a few distinct classes in and around cells, that damage spiraling out into a complex network of interacting downstream consequences. Fully understanding that network, fully understanding the progression of aging, will take the rest of this century, or longer. The root causes of aging, these forms of damage that arise from the normal operation of a youthful metabolism, are much less complex n comparison, and, at this time, are far better understood. Therapies resulting in large benefits, such as significant extension of healthy life and significant reversal of age-related disease, are more likely to arise from work on the causes of aging than from work on understanding the complicated progression of aging. That much is in the process of being demonstrated by senolytics that destroy senescent cells. Unfortunately, the research community is still largely focused on understanding the intricacies of aging, picking apart the details of the complex, damaged disarray of an aged metabolism, and aiming at no more than a modest slowing of aging. There is comparatively little interest in applying...
Source: Fight Aging! - Category: Research Authors: Tags: Activism, Advocacy and Education Source Type: blogs