Prognostic Value of Hypochloremia in Critically Ill Patients With Decompensated Cirrhosis

This study aimed to investigate the prognostic value of serum chloride and its association with mortality in cirrhotic patients. Design: Retrospective cohort study. Setting: The medical ICU at Parkland Memorial Hospital, a tertiary care public health system in Dallas, Texas. Patients: Adult patients with confirmed diagnosis of decompensated cirrhosis who were admitted to the ICU between March 2015 and March 2017. Interventions: None. Measurements and Main Results: Kaplan-Meier analysis and multivariable Cox proportional hazard ratio models were performed to determine the impact of hypochloremia on 180-day mortality. Of the 389 enrolled patients, 133 (34.2%) died within 180 days of ICU admission. Patients with hypochloremia had higher 180-day mortality than those with normochloremia (45.2% vs 26.7%; p
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research