Impact of NAVA Ventilation on Brain Oxygenation and Perfusion in Children With Congenital Heart Disease

Conditions:   Tetralogy of Fallot;   Hypoplastic Left Heart Syndrome;   Univentricular Heart;   Heart Defects, Congenital Interventions:   Other: Neurally adjusted ventilatory assist first;   Other: Conventional ventilation first Sponsor:   St. Justine's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

AbstractPurpose of ReviewEstablishing a diagnosis of ischemic heart disease (IHD) in women, including assessment for coronary microvascular dysfunction (CMD) when indicated, can be challenging. Access to performance of invasive testing when appropriate may be limited, and noninvasive imaging assessments have evolved. This review will summarize the various noninvasive imaging modalities available for the diagnosis of IHD and CMD in women, outlining indications, performance modalities, advantages, and limitations.Recent FindingsWhile stress echocardiography and single photon emission computed tomography (SPECT) myocardial pe...
Source: Current Atherosclerosis Reports - Category: Cardiology Source Type: research
AbstractPurpose of ReviewWe review the etiologies of neurodevelopmental outcomes in patients with congenital heart disease.Recent FindingsDevelopmental delays have been identified in patients with congenital heart disease (CHD). Though historically neurodevelopmental morbidity in patients with CHD was thought to be surgically related, recent advances in imaging technology and the ability to prospectively provide longitudinal follow-up indicate multiple complex etiologies of neurodevelopmental delay in this group. It has been suggested that alterations in cerebral perfusion is related to cerebral dysgenesis and immaturity. ...
Source: Current Pediatrics Reports - Category: Pediatrics Source Type: research
CONCLUSION: All reconstruction methods sistematically understimate EDV and ESV, with higher underestimation applying only the RR. No significant differences were observed between 4DM -RR and 4DM-FBP, for each parameter, when 4DM package was used. PMID: 32933466 [PubMed - as supplied by publisher]
Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research
AbstractTraditionally thought of primarily as the predominant regulator of myocardial perfusion, it is becoming more accepted that the human coronary microvasculature also exerts a more direct influence on the surrounding myocardium. Coronary microvascular dysfunction (CMD), not only precedes large artery atherosclerosis, but is associated with other cardiovascular diseases such as heart failure with preserved ejection fraction (HFpEF) and hypertrophic cardiomyopathy (HCM). It is also highly predictive of cardiovascular events in patients with or without atherosclerotic cardiovascular disease. This review focuses on this r...
Source: Microcirculation - Category: Research Authors: Tags: INVITED REVIEWS Source Type: research
AbstractComputed tomography coronary angiography (CTCA) has become a cornerstone in the diagnostic process of the heart disease. Although the cardiac imaging with interventional procedures is responsible for approximately 40% of the cumulative effective dose in medical imaging, a relevant radiation dose reduction over the last decade was obtained, with the beginning of the sub-mSv era in CTCA. The main technical basis to obtain a radiation dose reduction in CTCA is the use of a low tube voltage, the adoption of a prospective electrocardiogram-triggering spiral protocol and the application of the tube current modulation wit...
Source: La Radiologia Medica - Category: Radiology Source Type: research
AbstractTakotsubo syndrome (TTS) is a complex and still poorly recognized heart disease with a wide spectrum of possible clinical presentations. Despite its reversibility, it is associated with serious adverse in-hospital events and high complication rates during follow-up. Multimodality imaging is helpful for establishing the diagnosis, guiding therapy, and stratifying prognosis of TTS patients in both the acute and post-acute phase. Echocardiography plays a key role, particularly in the acute care setting, allowing for the assessment of left ventricular (LV) systolic and diastolic function and the identification of the t...
Source: Journal of Echocardiography - Category: Cardiology Source Type: research
Hypoplastic left heart syndrome (HLHS) is a complex form of congenital heart disease defined by anatomic and functional inadequacy of the left side of the heart with nonviability of the left ventricle to perform systemic perfusion. Lethal if not treated, a strategy for survival currently is well established, with continuing improvement in outcomes over the past 30  years. Prenatal diagnosis, good newborn care, improved surgical skills, specialized postoperative care, and unique strategies for interstage monitoring all have contributed to increasing likelihood of survival. The unique life with a single right ventricle ...
Source: Pediatric Clinics of North America - Category: Pediatrics Authors: Source Type: research
This study is a cross-sectional study. More than one thousand (N = 1012) patients referring to the Nuclear Medicine Department in Namazi Hospital, Shiraz, Iran, from March 2017 to March 2018 were studied. The patients' demographic data and their clinical history were collected. The results of the myocardial perfusion scan were recorded and compared between groups. Statistical analysis was implemented by SPSS version 18.0, and P values below 0.05 were considered statistically significant. Out of the 1012 patients participating in this study, 698 (69%) were female and 314 (31%) were male. Ischemic heart disease...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
AbstractPurpose of ReviewPET myocardial perfusion imaging (MPI) is an established modality for the evaluation of ischemic heart disease and quantitation of myocardial blood flow (MBF). New F-18-labelled radiopharmaceuticals have been recently developed to overcome some of the limitations of currently used tracers such as the need of an on-site cyclotron. The characteristics of the new tracers and the clinical results obtained so far will be reviewed.Recent FindingsMost of the interest in the field of18F-labelled radiotracers for PET MPI has been concentrated on MC-1 inhibitors, the prototype of which is18F-flurpiridaz. It ...
Source: Current Cardiology Reports - Category: Cardiology Source Type: research
Abstract Placental insufficiency, the main cause of Fetal Growth Restriction (FGR), is associated with adverse outcomes for both the mother and infant in the short term, but also with negative longer-term effects (such as heart disease, diabetes and stroke). Doppler Ultrasound is the main means of assessing placental function in clinical practice, but does not necessarily allow a precise distinction between placental insufficiency with secondary FGR, and normal placental function with a constitutionally small fetus. PMID: 32772422 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
More News: Brain | Cardiology | Children | Heart | Heart Disease | Hospitals | Neurology | Perfusion | Research