Head and Neck Squamous Cell Carcinoma in Marijuana Users

The legalization and increasing social acceptance of marijuana heightens the need for a better understanding of its potential role in the development of cancer. Studies suggest that a dose-dependent elevated cancer risk among marijuana users exists.3 It has also been demonstrated that cannabinoids promote the progression of human papilloma virus-related head and neck squamous cell carcinomas.2 Many of the present studies are limited by sample size, information regarding frequency and duration of use, as well as confounders, such as tobacco use.1 Further investigation of relationship between marijuana use and cancer of the head and neck will lead to a better understanding of the pathogenesis and potential sequelae of using this substance.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research