Atorvastatin Prevent the Neuron Loss in the Hippocampal Dentate Gyrus Region through its Anti-oxidant and Anti-apoptotic Activities.

CONCLUSION: Atorvastatin treatment in I/R rats decreases oxidative stress, production of ROS, apoptosis rate in neuronal cells, and improves the mitochondrial function. Hence, atorvastatin have a proper neuronal protective effect against the I/R injury in the brain. PMID: 32962624 [PubMed - as supplied by publisher]
Source: CNS and Neurological Disorders Drug Targets - Category: Drugs & Pharmacology Authors: Tags: CNS Neurol Disord Drug Targets Source Type: research