A Phase I Dose Escalation Study of Neoadjuvant SBRT plus Elective Nodal Radiation with Concurrent Capecitabine for Resectable Pancreatic Cancer.

and Purpose: The role of neoadjuvant radiation for resectable pancreatic adenocarcinoma is controversial. We performed a prospective dose-escalation study of neoadjuvant stereotactic body radiation therapy (SBRT) with concurrent capecitabine and elective nodal irradiation (ENI) followed by surgical resection to explore the toxicity and feasibility of this approach.

Source: International Journal of Radiation Oncology * Biology * Physics - September 13, 2020 Category: Radiology Authors: Jacob S. Witt, Aleksandra Kuczmarska-Haas, Meghan Lubner, Scott B. Reeder, Steve Y. Cho, Rebecca Minter, Sharon Weber, Sean Ronnekleiv-Kelly, Daniel Abbott, Noelle LoConte, Daniel L. Mulkerin, Sam J. Lubner, Nataliya V. Uboha, Dustin Deming, Mark A. Ritte Source Type: research