Clozapine for Treatment-Refractory Aggressive Behavior

AbstractEmergency psychiatry has the main role of resolving suicidal behavior and aggression. These severe psychiatric symptoms can be found in many psychiatric disorders such as schizophrenia, bipolar disorder, major depression, personality disorders, cognitive disorders, intellectual disability and substance abuse. Although indications for the use of antipsychotics are limited to a specific group of diseases, they are frequently used as rescue medication in high-risk or nonresponsive cases. Clozapine, the gold standard for TRS (treatment resistant schizophrenia) is effective in controlling aggression. The aim of the research was to identify the use of clozapine for treatment-refractory aggressive behavior in psychiatric emergency. A retrospective study based on the paper files of patients admitted between 2010 and 2019 in the Clinical Hospital of Psychiatry and Neurology of Brasov, Romania. Were included all the patients admitted as a psychiatric emergency and treated with clozapine for aggressive behavior. The hospital is an academic institution with 150 beds for acute patients, serving an area of over 600,000 inhabitants. It is the main public institution where patients with psychiatric emergencies are hospitalized. Off 19,000 patients admitted during the study period, 504 patients (2,4%) with a diagnosis other than schizophrenia or schizoaffective disorder received clozapine for aggressiveness (89.5%). The first four diagnoses identified were bipolar disorder (n =...
Source: Psychiatric Quarterly - Category: Psychiatry Source Type: research

Related Links:

In this study, we investigated the oscillatory hyperconnectivity and hypoconnectivity networks in MDD under a naturalistic and continuous stimuli condition of music listening. With the assumption that the healthy group and the MDD group share similar brain topology from the same stimuli and also retain individual brain topology for group differences, we applied the coupled nonnegative tensor decomposition algorithm on two adjacency tensors with the dimension of time $times $ frequency $times $ connectivity $times $ subject, and imposed double-coupled constraints on spatial and spectral modes. The music-induced oscillatory ...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - Category: Neuroscience Source Type: research
It's time to invest in housing for people intellectual disabilities
Source: Health Care:Physician Practices headlines - Category: American Health Source Type: news
AbstractThe USA has among the largest immigrant population of any country in the world, and over the past few decades, the proportion of Chinese immigrants in the USA has increased significantly. Immigrants may experience substantial acculturative stress as they learn to navigate their new environment, and this stress can contribute to depressive symptoms and poor mental health. Social support can help mitigate the effects of stress on depressive symptoms, but the protective effects of social support have been reported to differ between men and women. Thus, the present study examined associations of acculturative stress an...
Source: Journal of Racial and Ethnic Health Disparities - Category: International Medicine & Public Health Source Type: research
Source: Neuropsychiatric Disease and Treatment - Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
Describe the current state of the evidence regarding the relationships between different foods and food groups and the risk of depression.
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Late-Breaking Research Abstracts Source Type: research
Describe the prevalence of depression in relation to food security status in the United States.
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Late-Breaking Research Abstracts Source Type: research
Describe the biological, psychological, social, cultural, political, and economic determinants of eating behavior, and the associated opportunities and barriers to achieving optimal health and quality of life.
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Tuesday, October 19, 2021 Source Type: research
Describe how anxiety and depression may affect eating and physical activity behaviors among U.S. college students.
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Late-breaking Research Abstracts Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Conditions:   Cardiovascular Diseases;   Overweight;   Obesity;   Smoking;   Hypertension;   Cholesterol;   Diabetes Mellitus;   Prediabetic State;   Pregnancy;   Depression, Postpartum;   Depression;   Prevention;   Heart Disease Risk Factors Interventions:   Behavioral: Diabetes Prevention Program (DPP);   Behavioral: Reach Out, stay Strong, Essentials (ROSE);   Behavioral: Telephone Lifestyle Coaching Program (TLC) Sponsor:   VA Office of Research and Develo...
Source: - Category: Research Source Type: clinical trials
More News: Academia | Bipolar | Brain | Depression | Disability | Emergency Medicine | Hospitals | Mania | Neurology | Obsessive Compulsive Disorder | Postnatal Depression | Psychiatry | Romania Health | Schizophrenia | Study | Substance Abuse | Substance Abuse Disorders | Suicide