The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.
CONCLUSIONS: Genetic variations involving CYP11B2 might influence the kidney function, hypertension course, and severity via aldosterone secretion upregulation.
PMID: 32857720 [PubMed - as supplied by publisher]
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
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