The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.

CONCLUSIONS: Genetic variations involving CYP11B2 might influence the kidney function, hypertension course, and severity via aldosterone secretion upregulation. PMID: 32857720 [PubMed - as supplied by publisher]
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research