Science, Medical Groups Express Support for Fetal Tissue Research

The American Institute of Biological Sciences joined a coalition of 90 scientific, academic, and medical groups to express support for the continued use of human fetal tissue in biomedical research. In a July 28, 2020, letter to the National Institutes of Health (NIH) Human Fetal Tissue Research Ethics Advisory Board, the groups argued, in part: “The long-standing existing review process for fetal tissue research ensures that research using fetal tissue is scientifically meritorious, legal, and ethically sound. The legal framework for this research prohibits people from profiting from acquiring, receiving, or transferring fetal tissue for research. Each research proposal has already been favorably evaluated by subject matter experts on NIH study sections for scientific and technical merit, including significance, innovation, and approach. As the nation continues to respond to the coronavirus pandemic, we urge you to consider the potential of fetal tissue research to accelerate the development of new vaccines and viral therapies, not only for coronavirus but also for other incurable viral pathogens such as Zika and HIV. Fetal tissue research has the potential to accelerate the end to the pandemic, reduce human suffering, and enable the U.S. to better respond to future public health threats.” The coalition urged the board to consider the potential for fetal tissue research “to advance our understanding of human biology and the development of new treatments t...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news

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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Beth Israel Deacones Medical Center Coronavirus Johnson & Johnson Source Type: news
NEW BRUNSWICK, N.J., September 23, 2020 – Johnson &Johnson (NYSE: JNJ) (the Company) today announced the launch of its large-scale, pivotal, multi-country Phase 3 trial (ENSEMBLE) for its COVID-19 vaccine candidate, JNJ-78436735, being developed by its Janssen Pharmaceutical Companies. The initiation of the ENSEMBLE trial follows positive interim results from the Company’s Phase 1/2a clinical study, which demonstrated that the safety profile and immunogenicity after a single vaccination were supportive of further development. These results have been submitted to medRxiv and are due to be published online im...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Our Company Source Type: news
As the world faces the challenge of the COVID-19 pandemic, it has become an urgent need of the hour to understand how our immune system sense and respond to RNA viruses that are often life-threatening. While most vaccine strategies for these viruses are developed around a programmed antibody response, relatively less attention is paid to our innate immune defenses that can determine the outcome of a viral infection via the production of antiviral cytokines like Type I Interferons. However, it is becoming increasingly evident that the “cytokine storm” induced by aberrant activation of the innate immune response ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract SUMMARYIn recent decades, several new diseases have emerged in different geographical areas, with pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs). Recently, a new type of viral infection emerged in Wuhan City, China, and initial genomic sequencing data of this virus do not match with previously sequenced CoVs, suggesting a novel CoV strain (2019-nCoV), which has now been termed severe acute respiratory syndrome CoV-2 (SARS-CoV-2). Although coronavirus disease 2019 (COVID-19) is suspected to originate from an animal host (zoonotic origin) followed by human-to-human transm...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
Dr. Stephen Thomas, who helped develop vaccine candidates for diseases such as Ebola, Zika and MERS, discusses the challenges involved in accelerating development during a pandemic.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Tags: Healthcare /healthcare Innovation /innovation Science /science Business /business Policy /policy Editors' Pick editors-pick Decision Maker decision-maker Coronavirus Source Type: news
Discussions with the FDA are ongoing to define the required data set for filing Janssen’s Ebola vaccine regimen under the FDA’s Animal Rule licensure pathway. About Janssen’s Ebola Vaccine Regimen The Janssen investigational preventive Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo) utilizes a viral vector strategy in which viruses – in this case adenovirus serotype 26 (Ad26) and Modified Vaccinia Virus Ankara (MVA) – are genetically modified so that they cannot replicate in human cells. In addition, these vectors are modified to safely carry the genetic code of an Ebola virus protein in order...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
This article is part of #TIME100Talks: Finding Hope, a special series featuring leaders across different fields sharing their ideas for navigating the pandemic. Want more? Sign up for access to more virtual events, including live conversations with influential newsmakers.
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 TIME 100 TIME100 Talks video Source Type: news
According to a report by the New York Times, Dr. Rick Bright, a vaccine expert at the Department of Health and Human Services (HHS), has alleged that he was abruptly dismissed from his role overseeing an agency centrally involved in the process of developing and ultimately making available a coronavirus vaccine for questioning investments in anti-malarial drugs. Bright served as the Director of the Department of Health and Human Services’ Biomedical Advanced Research and Development Authority (BARDA) and Deputy Assistant Secretary for Preparedness and Response prior to his dismissal. He said he was “involunta...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
Abstract With the dramatic background of a newly emerged virus (SARS-CoV-2) spreading around the world, Coronavirus and other infectious health threats for the human and animal populations were illustrated and debated in excellent presentations at the IABS meeting 26-28 of February 2020. Historical evidence of pandemics and lessons learned from recent epidemics or epizootics caused by many pathogens (e.g., Ebola, Zika, and African Swine Fever viruses) illustrated the overarching need for close international cooperation. New and old technologies in vaccine development and their use were presented, resulting in a ca...
Source: Biologicals : Journal of the International Association of Biological Standardization - Category: Biotechnology Authors: Tags: Biologicals Source Type: research
NIH COVID-19 SIG Lecture Series NIAID has a long-standing dual mandate to maintain a robust portfolio of research in its key focus areas and to respond to emerging and re-emerging infectious diseases (EIDs). With this mandate, NIAID has also sought to improve EID-response preparedness, working in partnership with other U.S. government research entities, industry, academia, and international public-health organizations. This preparedness planning helped the institute respond rapidly to COVID-19. NIAID tapped existing coronavirus expertise and other assets to stand up research programs spanning basic virology and immunology ...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
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