Legionellosis in Japan: A Self-inflicted Wound?

Legionellosis in Japan: A Self-inflicted Wound? Intern Med. 2020 Jul 28;: Authors: Tanimoto T, Takahashi K, Crump A Abstract Legionellosis is a serious bacterial infection characterized by atypical pneumonia primarily due to infection with L. pneumophila, and bathing can be a potential cause of this infection. Legionellosis was first identified in 1977, and it is caused by Gram-negative bacteria belonging to the genus Legionella. Legionellosis remains an important public health threat, particularly in Japan, where the population is rapidly aging, thereby becoming more at risk for developing severe disease and accompanying life-threatening pneumonia. The bacteria are most commonly transmitted via the inhalation of contaminated aerosols produced and broadcast via water sprays, jets or mists. Infection can also occur via the aspiration of contaminated water or ice, or through inhalation of contaminated dust. Because the signs and symptoms of LD, as well as radiographic imaging are similar to pneumonia caused by other pathogens, a specific diagnostic test is required, such as a urine antigen detection test. Six clinical and laboratory parameters, a high body temperature, a non-productive cough, low serum sodium and platelet counts, and high lactate dehydrogenase (LDH) and c-reactive protein concentrations can be used to reliably predict the likelihood of LD. The first choices for chemotherapy are fluoroquinolone and macrolide antibiotic ...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research