High-dose 8% capsaicin patch in treatment of Chemotherapy-induced peripheral neuropathy (CIPN). A Systematic review.

This is a review of the evidence from studies of the efficacy and tolerability of topically applied, high-concentration (8%) capsaicin in Chemotherapy-induced peripheral neuropathy (CIPN). Methods: For this review, we searched EMBASE and MEDLINE to 14 April 2020. The terms used in the search included capsaicin patch, chemotherapy-induced peripheral neuropathy, cancer pain or malignant pain. Results: A total of 69 studies were obtained but only 5 were selected for the final analysis. Capsaicin 8% patch provides significant pain relief in CIPN, and may lead to regeneration and restoration of sensory nerve fibers.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research