Cancer Associated Fibroblasts (CAFs)-Flow Cytometry and Immunostaining Results

If they Walk and Talk Like CAFs, They Are!We are experiencing growing demand for are CAFs. They are closely associated with primary tumor cells and participate in the neoplastic process. There is reciprocal communication between CAFs and tumor cells through paracrine effects of secreted growth factors, cytokines & chemokines from both fibroblasts, tumor cells and other tumor-associated cells.Potential users are asking how well the cells are characterized. The purpose of this posting is to share key gene expression data: CELL LINES CD105 CD90 CD44 CD326 CD133 FAP SC00A1 (hMSCs) + + + - - - SC00A5 (pancreatic fibroblasts) + + + - - - CAF05 (colorectal CAFs) + + + - - + CAF07-AD (adenocarcinoma lung CAFs) + + + - - + CAF08 (Pancreatic Stellate CAFs) + + + - - + Table: expression of key proteinsImages: Human Lung Adenocarcinoma CAFs stained with Vimentin, aSMA, b-Catenin and DAPI (blue),Cancer Associated Fibroblasts Gene Expression Data(pdf - 784Kb)-Flow Cytometry and Immunostaining Results.Questions? Please contact me directly-Pete Shuster- CEO & Owner-pshuster@neuromics.com or 612-801-1007.
Source: Neuromics - Category: Neuroscience Tags: Adenocarcinoma CAFs Cancer Associated Fibroblasts colorectal CAFs Colorectal Cancer Pancreatic Fibrioblasts Pancreatic Stellates Source Type: news