133 The relationship between FGFR1 and mevalonate in adiposity-associated cancer: Implications of statins for chemoprevention

The relationship between excess adiposity and skin cancer risk is not fully understood. Studies demonstrate an inverse correlation between non-melanoma skin cancer (NMSC) and excess body weight, as assessed by body mass index (BMI). However, the Swedish Obese Subjects study demonstrated that bariatric surgery was associated with a reduced risk of both melanoma and NMSC. Based upon these opposing findings, further studies are warranted to understand how excess adiposity influences skin carcinogenesis.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Carcinogenesis and Cancer Genetics Source Type: research