Long non-coding RNA MINCR aggravates colon cancer via regulating miR-708-5p-mediated Wnt/ β-catenin pathway.

CONCLUSION: MINCR sponges miR-708-5p to up-regulate CTNNB1 and activate Wnt/β-catenin pathway, thus promoting the development CC. Targeting MINCR might shed new light on the therapeutic strategies of CC.
PMID: 32535381 [PubMed - as supplied by publisher]

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 10, 2020 Category: Drugs & Pharmacology Authors: Yu Y, Chang Z, Han C, Zhuang L, Zhou C, Qi X, Peng Z Tags: Biomed Pharmacother Source Type: research