Evaluation of Diagnostic Accuracy Following the Coadministration of Delta-Aminolevulinic Acid and Second Window Indocyanine Green in Rodent and Human Glioblastomas

ConclusionOur results provide the first direct comparison of the diagnostic utility of SWIGvs 5-ALA in both rodent and human HGG. Given the broader clinical utility of SWIG compared with 5-ALA, our data supports the use of SWIG in tumor surgery to improve the extent of safe resections.Clinical TrialNCT02710240 (US National Library of Medicine Registry;https://www.clinicaltrials.gov/ct2/show/NCT02710240?id=NCT02710240&draw=2&rank=1).

Source: Molecular Imaging and Biology - June 7, 2020 Category: Molecular Biology Source Type: research