Cancers, Vol. 12, Pages 1478: Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma

Conclusion. Meningiomas are not very amenable to PDOX modeling, for reasons that remain unclear. Yet at least some of the most malignant tumors can be modeled, and cryopreserved primary tumor cells can create large panels of tumors that can be used for preclinical drug testing.

Source: Cancers - June 4, 2020 Category: Cancer & Oncology Authors: Huiyuan Zhang Lin Qi Yuchen Du L. Frank Huang Frank K. Braun Mari Kogiso Yanling Zhao Can Li Holly Lindsay Sibo Zhao Sarah G. Injac Patricia A. Baxter Jack M. Su Clifford Stephan Charles Keller Kent A. Heck Akdes Harmanci Arif O. Harmanci Jianhua Yang Tie Tags: Article Source Type: research