Acute kidney injury: an unexpected Isoniazid-related adverse event in a patient with Crohn's disease receiving prophylactic treatment for latent tuberculosis

We have recently observed a case of acute kidney Injury (AKI) in a patient with Crohn's disease (CD) receiving isoniazid (INH) prophylaxis for latent tuberculosis infection (LTBI). While the most common INH-related adverse events are well-known and include asymptomatic elevation of serum liver enzyme concentrations, peripheral neuropathy and hepatotoxicity, INH-induced AKI is a very rare event that has been occasionally reported in the literature particularly in pediatric patients [1-3].

Source: Digestive and Liver Disease - June 2, 2020 Category: Gastroenterology Authors: Fabiola De Biasio, Annalisa Aratari, Sara Caporuscio, Iole Simeoni, Claudio Papi, Stefano Festa Tags: Correspondence Source Type: research