Safety, Tolerability and Pharmacokinetics of Vidofludimus calcium (IMU-838) After Single and Multiple Ascending Oral Doses in Healthy Male Subjects

ConclusionOverall, oral IMU-838 was generally well tolerated in SAD and MAD studies in healthy subjects over a wide dose range of 10 –50 mg. IMU-838 was well absorbed after single daily doses. IMU-838 showed dose proportional pharmacokinetics after single and multiple oral dosing.

http://link.springer.com/10.1007/s13318-020-00623-7

Source: European Journal of Drug Metabolism and Pharmacokinetics - May 1, 2020 Category: Drugs & Pharmacology Source Type: research