Viruses, Vol. 12, Pages 490: Distribution and Genetic Variability of Sapoviruses in Africa
Viruses, Vol. 12, Pages 490: Distribution and Genetic Variability of Sapoviruses in Africa
Viruses doi: 10.3390/v12050490
Authors:
Kgomotso Makhaola
Sikhulile Moyo
Lemme P. Kebaabetswe
In this review, we describe the distribution and genetic diversity of sapoviruses detected among humans, animals and the environment in African countries. Databases were searched for studies conducted in African countries and published between Jan 2005 and Mar 2019. Only studies where RT- PCR was used for initial detection were included in the systematic review. We identified 27 studies from 14 African countries with 18 focused on human sapoviruses, two on animal sapoviruses and seven on sapoviruses observed in the environment. Samples. The overall estimated pooled prevalence of human sapovirus infections among symptomatic and asymptomatic individuals was similar at 5.0% (95% Confidence Interval (CI): 3.0–7.0) and 2.0% (95% CI: 1.0–3.0), respectively. In environmental samples sapovirus detection rates ranged from 0% to 90% while in animal studies it was 1.7% to 34.8%. Multiple causes of gastroenteritis, sensitivity of detection method used, diversity of sapovirus strains and rotavirus vaccine coverage rate are some of the factors that could have contributed to the wide range of sapovirus detection rates that were reported. The studies reported human genogroups GI, GII, and GIV, with genogroup GI being the most prevalent. Some potential novel strains were ...
Source: Viruses - Category: Virology Authors: Kgomotso Makhaola Sikhulile Moyo Lemme P. Kebaabetswe Tags: Review Source Type: research
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