Head and neck metachronous tumors - clinical, histopathological and immunohistochemical study.

Head and neck metachronous tumors - clinical, histopathological and immunohistochemical study. Rom J Morphol Embryol. 2019;60(4):1199-1206 Authors: Moţ IC, Poenaru M, Mogoantă CA, Istrate-Ofiţeru AM, Oprişcan IC, Sarău CA, Mănescu MD, Enăchescu V, Dogaru CA, Popescu C, Morar R, Balica NC, Horhat ID Abstract Multiple primary tumors (MPT) represent an important factor affecting the survival of some patients. They present an incidence of about 0.7-11% of all carcinomas developing in any region of the human body, being either synchronous or metachronous. These tumors raise problems of differential diagnosis, with tumoral relapses and distance metastases; also, they involve problems related to chemotherapy, radiotherapy and surgical treatment. In the present paper, we studied a group of 902 patients diagnosed with head and neck tumors admitted to the Ear, Nose & Throat (ENT) Clinic of the Emergency County Hospital of Timişoara, Romania, and we identified 12 patients with metachronous tumors, representing 1.33% of the hospitalized cases. Of the 12 patients with metachronous tumors, a single case was a woman, the other 11 cases being diagnosed in men. Regarding the age of the patients with metachronous tumors, only a single patient was aged less than 60 years old; most of them (nine patients) were aged between 60 and 69 years old, while two patients were aged over 70 years old. Nine patients were alcohol consumers, while 10 (83....
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research