Fetal Cerebral Vascular Response to Maternal Hyperoxia in Congenital Heart Disease: Effects of Cardiac Physiology.

CONCLUSIONS: The fetal cerebral vascular response to MH varies based on underlying CHD diagnosis, suggesting that cardiovascular physiology may influence autoregulatory capacities of the fetal brain. Further studies are needed to determine clinical implications of these findings on long-term neurodevelopment in these at-risk children. This article is protected by copyright. All rights reserved. PMID: 32202689 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research

Related Links:

This study presents the first in vivo validation of fetal vessel T2 oximetry against the in vitro T2-SO2 relationship using catheterized sheep fetuses and compares the normal SO2 in the major vessels between the human and sheep fetal circulations. Human fetal vessel SO2 by T2 MRI confirms many similarities with the sheep fetal circulation and is able to demonstrate regional differences in SO2 , in particular the significantly higher SO2 in the left versus right heart. ABSTRACT: Blood T2 magnetic resonance imaging (MRI) relaxometry non-invasively measures oxygen saturation (SO2 ) in major vessels but has not been valid...
Source: The Journal of Physiology - Category: Physiology Authors: Tags: J Physiol Source Type: research
To investigate the association between pathogenic copy number variants (p-CNVs) and abnormal karyotypes detected by chromosomal microarray analysis (CMA) and echogenic intracardiac focus (EIF). This was a retrospective study of fetuses with EIF with CMA data at the Prenatal Diagnosis Center of the West China Second University Hospital of Sichuan University between September 2014 and May 2017. Fetuses were assigned to the isolated EIF and non-isolated EIF groups according to the presence of other ultrasound abnormalities. Among 244 pregnant women, there were 143 cases of isolated EIF and 101 of non-isolated EIF. CMA revea...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
We describe the clinical features of a four-year-old male child with a 139 kb deletion at 7p22.3 involving SNX8 gene, inherited from a mosaic mother. The same deletion is also present in the fetus on the ongoing third pregnancy of the couple with normal fetal ultrasound assessment. The proband was prenatally diagnosed with left kidney agenesis. He does not show any congenital heart disease, but mild intellectual disability, learning and language delay, and severe behavioral problems related to the hyperactive-impulsive and inattentive area. These clinical features are also evident in other 7p22 deletions cases involving ...
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Eur J Med Genet Source Type: research
In this study, we compared the types of congenital heart malformation, accompanying diseases and fetal outcomes in the first and second trimesters of pregnancy to clarify the advantage of early screening. From January 2013 to June 2018, 230 fetuses were diagnosed with congenital heart malformations using ultrasound method in Qilu Hospital of Shandong University, and divided into 2 groups:the first trimester fetuses (group A) and the second trimester fetuses (group B). In addition, we collected and organized medical data of 347 cases diagnosed with congenital heart disease during 1998 to 2005 (group C). We compared the s...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
The objectives were to examine pregnancy outcomes in adolescent primigravida and to determine the effects of adolescent pregnancy on pregnancy-induced hypertension (PIH). A retrospective analysis of pregnancy outcomes was carried out in 2440 adolescent primigravida, compared with 14,259 primigravida aged 20-29 years. The adolescents had significantly higher rates of maternal death, maternal heart disease, PIH, puerperal infection, chorioamnionitis, urinary tract infection, foetal anomaly, preterm delivery, low birth weight, low Apgar scores and stillbirth. Multivariate logistic regression analysis showed that both old...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Abstract Objective To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation. Methods A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morph...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Current guidelines recommend a fetal echocardiogram only upon abnormal fetal cardiac findings on ultrasound and in pregnancies with identified risk factors. However, prenatal detection for congenital heart disease (CHD) is estimated to be 30-50%. Identifying CHD in utero results in a higher probability of being delivered at a tertiary care center and better neonatal outcomes. The purpose of this study was to determine whether universal screening for all pregnant women with fetal echocardiogram is cost effective when compared with current guidelines.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session IV Source Type: research
Ultrasound in Obstetrics&Gynecology,Volume 0, Issue ja, -Not available-.
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: Source Type: research
CONCLUSION: RV dysfunction before pregnancy seems to impact placentation resulting in increased resistance in the uterine arteries flow, already detectable from the first trimester. This is, in turn, associated with pregnancy complications. Early monitoring of UPF might be useful in women with pre-existing subclinical RV dysfunction to identify pregnancies in need of an even closer obstetrical surveillance. This article is protected by copyright. All rights reserved. PMID: 30334300 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
More News: Brain | Cardiology | Cardiovascular | Children | Heart | Heart Disease | Neurology | OBGYN | Physiology | Pregnancy | Radiology | Study | Ultrasound | Women