Assessment of vitamin D and inflammatory markers profile in cardiac tissue on Parkinson disease animal model.

CONCLUSION: Our findings suggest a link between cardiac tissue changes and cardiac functional changes early after the central dopaminergic damage induced by 6-OHDA. Knowledge of the cardiac abnormalities in the 6-OHDA model is critical in identifying future therapeutic targets and disease-modifying approaches for PD non-motor features.
PMID: 32124387 [PubMed - as supplied by publisher]

Source: Pharmacological Reports - March 1, 2020 Category: Drugs & Pharmacology Authors: Nejm MB, Guimarães-Marques MJ, Oliveira LF, Damasceno L, Andersen ML, Tufik S, Fonseca F, Olszewer E, Leça R, de Almeida ACG, Scorza FA, Scorza CA Tags: Pharmacol Rep Source Type: research