Depression and suicidal ideation among patients with cancer in the United States: a population-based study - Abdel-Rahman O.

PURPOSE: To evaluate the association between cancer diagnosis and depression and suicidal ideation in a population-based cohort in the United States. METHODS: This was a cross-sectional study based on the National Health and Nutrition Examination S...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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In conclusion, lithium confers protection to the skeleton but its clinical utility awaits further validation from human clinical trials.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Authors: Bottino LG, Fuchs FD Abstract Introduction: Angiotensin receptor blockers (ARBs) are recommended as preferential drugs in the treatment of hypertension by guidelines. In this review, we reappraise their effectiveness to preventing major cardiovascular outcomes and the recent concerns with new adverse effects.Areas covered: ARBs were not superior to placebo in the prevention of all-cause deaths and combined cardiovascular events in seven randomized controlled trials (RCT). Several meta-analyses, with large number of participants, confirmed these findings. Three RCT trials, published in top journals, were re...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
ConclusionsResveratrol could synergistically enhance the killing effect of TK/GCV suicide gene system in melanoma B16 cells and transplanted melanoma. It might be a promising adjuvant of TK/GCV therapy.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Authors: Ludvigsson J Abstract The negative consequencies of diabetes treatment are traditionally regarded as caused by a disastrous treatment rather than adverse events of the insulin preparations. However, hypoglycemia, changes at the injection site (lipatrophy, lipoma), insulin allergy, obesity and increased risk of certain forms of cancer can easily be regarded as adverse events of the drug, and needle-phobia, psychological problems, increased risk of suicide are adverse events related to insulin and its administration. Also macroangiopathy and even microangiopathy to some extent can be regarded as adverse even...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
Abstract Elucidating the mechanism underlying osteoclast differentiation is important to improve our understanding of the pathophysiologies related to skeletal diseases and osteolytic metastasis in cancer. Sex-determining region Y-box containing gene 2 (SOX2), a stemness marker, is known to affect osteoblast differentiation and cancer metastasis. However, its role in osteoclastogenesis has not been investigated to date. Here, we report that SOX2 protein and mRNA expression was upregulated during osteoclast differentiation. The overexpression or knockdown of SOX2 in osteoclast precursor cells enhanced or suppressed...
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Tags: Biochem Biophys Res Commun Source Type: research
A brief look at the most recent death statistics from the CDC tells us that 74% of the deaths in the US are due to 10 causes: heart disease, cancer, injuries, chronic lower respiratory disease, stroke and cerebrovascular diseases, Alzheimer's disease, diabetes, influenza and pneumonia, kidney disease, and suicide.1 So it comes as no surprise that many of us, as health care providers, are often consumed with treating disease, rescuing a patient from the jaws of death, and improving the quality of life for those who are afflicted by multiple comorbidities.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research
ConclusionsThese CD-TK-CNBs may become a novel treatment for bladder cancer.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
BACKGROUND The suicide risk of patients with cancer is higher than the general population. Our research aimed to explore the Surveillance, Epidemiology, and End Results (SEER) database to define incidence and quest risk factors for death of suicide in pati...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Head and neck cancer survivors (HNCS) suffer from high rates of chronic pain, substance use, and mental health comorbidities. HNCS have one of the highest rates of suicide among patients with cancer and are almost twice as likely to die by suicide compared to other cancer survivors. Among a national cohort of Veteran HNCS, we examined the associations between chronic pain, mental health and substance use disorder (SUD) diagnoses, and engagement in mental health services with risk of suicidal self-directed violence (SSDV), which included both suicide attempts and death by suicide.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: K. Kian Ang, MD, PhD, FASTRO, Commemorative Plenary Session Source Type: research
CONCLUSIONS Clinicians and caregivers can apply our findings to identify KS patients with high suicide risk characteristics (white race, age of 18-44 years, non-chemotherapy) and exert timely interventions during patient diagnosis, treatment, and follow-up to reduce the suicide rate in this population. PMID: 32148334 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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