Potential of the zebrafish model for the forensic toxicology screening of NPS: a comparative study of the effects of APINAC and Methiopropamine on the behavior of zebrafish larvae and mice.

In conclusion, the present study highlighted the impairment of spontaneous motor and sensorimotor behavior induced by MPA and APINAC administration in both species, thus confirming the usefulness of ZL as a model for a rapid behavioural-based drug screening.
PMID: 32050087 [PubMed - as supplied by publisher]

Source: Neurotoxicology - February 8, 2020 Category: Neurology Authors: Morbiato E, Bilel S, Tirri M, Arfè R, Fantinati A, Savchuk S, Appolonova S, Frisoni P, Tagliaro F, Neri M, Grignolio S, Bertolucci C, Marti M Tags: Neurotoxicology Source Type: research