Association between trace elements in serum from bipolar disorder and schizophrenia patients considering treatment effects

ConclusionsThe obtained results suggest that the imbalance in Fe concentrations is an effect of BD treatment. Lithium is supposed to have an antagonist effect for Se in BDL patients. A negative correlation reported between Fe and BMI in SCZ group could be related to antipsychotic treatment and the Cu/Zn ratio reported could be considered as a suggesting parameter to relate oxidative stress to SCZ. Future studies including larger number of patients with SCZ and BD before and after treatment are necessary to confirm the investigative results presented herein.
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research