LncRNA LINC00662 promotes colon cancer tumor growth and metastasis by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway.

CONCLUSION: LINC00662 overexpression promoted the occurrence and development of colon cancer by competitively binding with miR-340-5p to regulate CLDN8/IL22 co-expression and activating ERK signaling pathway. PMID: 31900207 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31900207?dopt=Abstract

Source: Cell Research - January 2, 2020 Category: Cytology Authors: Cheng B, Rong A, Zhou Q, Li W Tags: J Exp Clin Cancer Res Source Type: research