Deformational changes after convection-enhanced delivery in the pediatric brainstem.

CONCLUSIONS: CED infusion into the brainstem correlates with immediate but self-limited deformation changes in the pons. The persistence of increased ventricular volume and no need for CSF diversion post-CED are inconsistent with obstructive hydrocephalus. Defining the degree and time course of these deformational changes can assist in the interpretation of neuroimaging along the DIPG disease continuum when CED is incorporated into the treatment algorithm.
PMID: 31896089 [PubMed - in process]

Source: Neurosurgical Focus - December 31, 2019 Category: Neurosurgery Authors: Bander ED, Tizi K, Wembacher-Schroeder E, Thomson R, Donzelli M, Vasconcellos E, Souweidane MM Tags: Neurosurg Focus Source Type: research