Identification of RNPC3 as a novel JAK2 fusion partner gene in B ‐acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib

ConclusionThis finding adds to the expanding compendium ofJAK2 fusions found in B ‐ALL and suggests the potential need for a diagnostic FISH analysis as well as RNA‐Seq in the appropriate clinical setting.

Source: Molecular Genetics & Genomic Medicine - December 29, 2019 Category: Genetics & Stem Cells Authors: Xue Chen, Fang Wang, Yang Zhang, Xiaoli Ma, Mingyue Liu, Panxiang Cao, Lin Zhou, Lan Wang, Xian Zhang, Tong Wang, Hongxing Liu Tags: ORIGINAL ARTICLE Source Type: research