Hsa_circ_0006948 enhances cancer progression and epithelial-mesenchymal transition through the miR-490-3p/HMGA2 axis in esophageal squamous cell carcinoma.

In conclusion, hsa_circ_0006948 was overexpressed in ESCC tissues and promoted cancer progression, and it could induce EMT by enhancing HMGA2 by sponging miR-490-3p, suggesting that hsa_circ_0006948 could be a biomarker for ESCC. PMID: 31881015 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31881015?dopt=Abstract

Source: Aging - December 25, 2019 Category: Biomedical Science Authors: Pan Z, Lin J, Wu D, He X, Wang W, Hu X, Zhang L, Wang M Tags: Aging (Albany NY) Source Type: research