Examining the effects of a high-protein total diet replacement on energy metabolism, metabolic blood markers, and appetite sensations in healthy adults: protocol for two complementary, randomized, controlled, crossover trials

DiscussionThis will be the first inpatient metabolic balance study examining the impact of a high-protein total diet replacement on energy metabolism, metabolic blood markers and appetite sensations in healthy young adults (of both sexes) using a whole-body calorimetry unit. Results of this clinical trial can ultimately be used to develop strategies to optimize high-protein diet interventions and weight management.Trial registrationClinicalTrials.gov Identifiers:NCT02811276 (registered on 16 June 2016) andNCT03565510 (registered on 11 June 2018).Protocol versionNCT02811276: version 10 (2 March 2018); NCT03565510: version 3 (28 September 2018).
Source: Trials - Category: Research Source Type: clinical trials