Intermittent cholecalciferol supplementation in children and teenagers followed in pediatric nephrology: data from a prospective single-center single-arm open trial

Conclusion: This vitamin D supplementation protocol using intermittent moderate doses of cholecalciferol seems efficient in 54% of cases, with neither significant overdose nor hypercalciuria.What is Known:•Vitamin D deficiency is frequent in pediatric nephrology.•The 2017 European guidelines recommend keeping 25OH vitamin D levels within the 75 –120 nmol/L range ideally with daily supplementation, but intermittent supplementation with D3 has also been proposed.What is New:•We assessed the influence of a local protocol of intermittent vitamin D supplementation on the evolution of 25-D levels between baseline and 2  months in children and teenagers followed in pediatric nephrology.•The intermittent cholecalciferol supplementation protocol seems efficient in 54% of cases, with neither significant overdose nor hypercalciuria.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research