Common variable immunodeficiency presenting as sarcoidosis in a 9 ‐year‐old child

ConclusionCommon variable immunodeficiency is a heterogeneous condition with a highly variable clinical phenotype and a strong association with autoimmune disorders. The presence of noncaseating granuloma and pulmonary lesions, along with extrapulmonary features required a step by step approach to differentiate between CVID and sarcoidosis. This enables early introduction of immunoglobulin replacement therapy and decreases the morbidity and mortality of CVID.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: APLAR GRAND ROUND CASE Source Type: research

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This study aimed to evaluate the prevalence of internal symmetry (the number and morphology of root canals) in the mandibular incisors using cone beam computed tomography (CBCT). A total of 302 CBCT scans involving 1,208 mandibular incisors were evaluated using the Vertucci's classification regarding the number and configuration of root canals. The central mandibular incisors exhibited two root canals in 22.6% of patients and lateral incisors in 24.3% of patients. Most teeth (76.4%) had a type I configuration (a single root canal, 1-1), 21.7% had type II (2-1), 1.1% had type V (1-2), and 0.8% had type IV (2-2). Teeth with ...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
This report presents a case where sinus floor elevation was performed using tricalcium phosphate (TCP) plates supported by implant bodies, and only the blood clot was present around the implant bodies. Cone-beam computed tomography images, taken one year after the lateral approach, revealed the presence of a TCP-like radio-opacity, which almost disappeared after two years. About seven years after the surgery, the patient's superstructure and occlusion were stable. Furthermore, the grafted TCP was completely absorbed, and the implant body appeared to be in good condition, with no signs of bone resorption around the implant....
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
Publication date: Available online 31 March 2020Source: Diagnostic and Interventional ImagingAuthor(s): L. Perrier, P. Feugier, C. Goutain-Majorel, N. Girouin, R. Boutier, M. Papillard, M. Bedel, M. Rabilloud, O. Rouvière
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Conclusions: Valganciclovir appears effective and safe for treating CMVAU in this retrospective case series. Long-term antiviral prophylaxis does not abolish recurrences, although it may possibly reduce their frequency when compared with no prophylaxis.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: This study shows significant differences between both insertion techniques regarding correct graft orientation directly after graft implantation leading to prolonged insertion-to-attachment time when the graft is flushed instead of pushed into the anterior chamber.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
de Oliveira Reis, Bruna / de Lima Godas, Andr é Gustavo / Suzuki, Thaís Yumi Umeda / Tozzi, Ticiane Cestari Fagundes / Briso, André Luiz Fraga / dos Santos, Paulo HenriquePage 145 - 152Purpose: To evaluate the microtensile bond strength of dentine/self-adhesive resin cement interface after several treatments on a dentine surface.Materials and Methods: Twenty-eight human molars were selected and divided into four groups: no treatment (control (C)); 2% chlorhexidine digluconate (CHX); 25% polyacrylic acid (PA); and 23 ppm dispersive solution of silver nanoparticle (SN). Prepolymerised TPH resin composite...
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research
Authors: Esch T, Stefano GB, Ptacek R, Kream RM Abstract Over the past two decades, a major goal of our research group has been elucidation of the functional roles of several key regulatory molecules in proinflammatory preconditioning involved in the pathophysiology of seemingly diverse human disease states. By necessity, operational definitions of proinflammation must be intrinsically fluid based on recent advances in our understanding of complex regulation of innate and adaptive immune processes. Similar to systemic acute stress, a physiological proinflammatory state appears to be a key autoregulatory mechanism f...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
A group of moderately ill people were given hydroxychloroquine, which appeared to ease their symptoms quickly, but more research is needed.
Source: NYT - Category: American Health Authors: Tags: Coronavirus (2019-nCoV) Hydroxychloroquine (Drug) Drugs (Pharmaceuticals) Quarantines Shortages Autoimmune Diseases Pneumonia Immune System Malaria Schaffner, William your-feed-healthcare Source Type: news
Authors: Ventura CG, Roque FL, Sousa IQ, Lobo RD, Luders C Abstract INTRODUCTION: Chronic hemodialysis (HD) patients are considered to be at high risk for infection. Here, we describe the clinical outcomes of chronic HD patients with influenza A (H1N1) infection and the strategies adopted to control an outbreak of influenza A in a dialysis unit. METHODS: Among a total of 62 chronic HD patients, H1N1 infection was identified in 12 (19.4%). Of the 32 staff members, four (12.5%) were found to be infected with the H1N1 virus. Outcomes included symptoms at presentation, comorbidities, occurrence of hypoxemia, hospit...
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
This article is very much important to each and every one of us. Please read and retweet it. COVID-19: Further Evidence that the Virus Originated in the US.— Lijian Zhao 赵立坚 (@zlj517)March 13, 2020This deliberate disinformation was met withcalls for Twitter to remove Zhao ’s tweets. Twitter refrained from removing the tweets but posted an update to their misinformation policies,stating: “Official government accounts engaging in conversation about the origins of the virus and global public conversation about potential emergent treatments will be permitted, unless the content co...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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