Common variable immunodeficiency presenting as sarcoidosis in a 9 ‐year‐old child

ConclusionCommon variable immunodeficiency is a heterogeneous condition with a highly variable clinical phenotype and a strong association with autoimmune disorders. The presence of noncaseating granuloma and pulmonary lesions, along with extrapulmonary features required a step by step approach to differentiate between CVID and sarcoidosis. This enables early introduction of immunoglobulin replacement therapy and decreases the morbidity and mortality of CVID.

Source: International Journal of Rheumatic Diseases - December 18, 2019 Category: Rheumatology Authors: Ilaria Maccora, Edoardo Marrani, Silvia Ricci, Chiara Azzari, Gabriele Simonini, Rolando Cimaz, Teresa Giani Tags: APLAR GRAND ROUND CASE Source Type: research