Riluzole is a Promising Pharmacological Inhibitor of Bilirubin-Induced Excitotoxicity in the Ventral Cochlear Nucleus.

CONCLUSIONS AND IMPLICATIONS: These data suggest that riluzole can protect neurons in the ventral cochlear nucleus from bilirubin-induced hyperexcitation and excitotoxicity through reducing presynaptic glutamate release.
PMID: 25495717 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - December 12, 2014 Category: Neuroscience Authors: Han GY, Li CY, Shi HB, Wang JP, Su KM, Yin XL, Yin SK Tags: CNS Neurosci Ther Source Type: research