Extract of common mallow (Malvae sylvestris) enhances growth, immunity, and resistance of rainbow trout (Oncorhynchus mykiss) fingerlings against Yersinia ruckeri infection

We reported higher values of hematocrit, hemoglobin, Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Volume (MCV), White Blood Cell (WBC), Red Blood Cell (RBC) and lymphocytes for treated groups. Innate immune responses (Alternative complement activity (ACH50) in M2 and M3 group, total Immunoglobulin (Ig) and lysozyme in M3), mucosal immune parameters (ACH50, total Ig for M2 and M3 group and lysozyme in all treated groups) were enhanced. Activities of digestive enzymes (protease in all treated groups, amylase for 3 and 5%, while lipase only for 5%) and lower activity of liver ALT enzyme in individuals treated with highest dose was observed. Overall results indicated that the extract can positively affect growth performance and immune responses of rainbow trout.
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research

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CONCLUSIONS Our results highlight that interaction of Nr4a1 and LKB1 can mitigate T2DM by activating the AMPK/SIRT1 signaling pathway and inhibiting NF-kappaB activation. This may offer new insight for T2DM treatment. PMID: 31939452 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Copper oxide nanoparticles (CuO NPs) use has exponentially increased in various applications (such as industrial catalyst, gas sensors, electronic materials, biomedicines, environmental remediation) due to their flexible properties, i.e. large surface area to volume ratio. These broad applications, however, have increased human exposure and thus the potential risk related to their short- and long-term toxicity. Their release in environment has drawn considerable attention which has become an eminent area of research and development. To understand the toxicological impact of CuO NPs, this review summarises the in-vitro and ...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
The study aims to document the effect of starch-stabilised copper-based nanoparticles (CuNPs) on the biosynthesis of pharmaceutically valuable secondary metabolites, especially saponins, of the reputed nootropic herb Bacopa monnieri (L.) Pennell. CuNPs were synthesised chemically by the reduction of cupric sulphate pentahydrate with ascorbic acid using starch as the capping agent. They were characterised by UV–visible spectrophotometry, Fourier-transform infra-red spectroscopy, X-ray diffraction, high-resolution transmission electron microscopy and zeta potential. The nanoparticles consisted of cuprous oxide and meta...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
This study reported a simple and inexpensive method for determination of 10-hydroxy-2-decenoic acid (10-HDA) and free amino acids in different royal jelly based dietary supplement samples using a purpose-made dual-channeled capillary electrophoresis (CE) system with capacitively coupled contactless conductivity detection (C4D). The objective of the work is to propose a tool for food / quality control activities that can be realizable even with a modest infrastructure. 10-HDA and free amino acids were analyzed using the background electrolyte (BGE) solutions composed of 20 mM Tris(hydroxymethyl)aminomethane adjusted ...
Source: Journal of Food Composition and Analysis - Category: Food Science Source Type: research
Publication date: Available online 16 January 2020Source: Journal of Food Composition and AnalysisAuthor(s): Tereza Slámová, Anna Sadowska-Rociek, Adéla Fra┼łková, Magdalena Surma, Jan BanoutAbstractThe aim of this study was to develop an effective sample preparation procedure for the determination of polycyclic aromatic hydrocarbons (PAHs) in smoked fatty products of animal origin (fish, cheese and sausage). Two different approaches were tested: classical QuEChERS and procedure with the use of Enhanced Matrix Removal (EMR)-Lipid material. Two techniques of extract preconcentration: under nitrog...
Source: Journal of Food Composition and Analysis - Category: Food Science Source Type: research
Publication date: Available online 15 January 2020Source: Plant ScienceAuthor(s): Courtney P. LeisnerAbstractAnthropogenic increases in fossil fuel emissions have been a primary driver of increased concentrations of atmospheric carbon dioxide ([CO2]) and other greenhouse gases resulting in warmer temperatures, alterations in precipitation patterns, and increased occurrence of extreme weather events in terrestrial areas across the globe. In agricultural growing regions, alterations in climate can challenge plant productivity in ways that impact the ability of the world to sustain adequate food production for a growing and i...
Source: Plant Science - Category: Biology Source Type: research
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Source: Critical Reviews in Toxicology - Category: Toxicology Authors: Source Type: research
Publication date: Available online 16 January 2020Source: Journal of Hazardous MaterialsAuthor(s): Yaoping Hu, Zhijin GaoABSTRACTCrystal violet (CV), a hazardous dye, poses a serious threat to the environment and human health. This motivates us to develop a facile method for its sensitive detection. Herein, we demonstrate a rapid sensing of CV using a novel fluorescent nanomaterial, yellow emissive Se,N-codoped carbon dots (CDs). CDs with an intense photoluminescence peak at 566 nm are synthesized by a hydrothermal technique using selenourea and o-phenylenediamine as precursors. This material shows a high quantum yi...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
In this study, a targeted metabolomics approach was used to investigate the toxic mechanisms of endosulfan sulfate in adult zebrafish using the multiple reaction monitoring mode of a GC-MS/MS. The LC50 of endosulfan sulfate in adult zebrafish was determined and then zebrafish were exposed to endosulfan sulfate at one-tenth the LC50 (0.1LC50) or the LC50 for 24 and 48 hours. After exposure, the fish were extracted, derivatized and analyzed by GC-MS/MS for 379 metabolites to identify 170 metabolites. Three experimental groups (control, 0.1LC50 and LC50) were clearly separated in PLS-DA score plots. Based on the VIP, A...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Alessandro Poggi1*, Roberto Benelli2, Roberta Venè1, Delfina Costa1, Nicoletta Ferrari1, Francesca Tosetti1 and Maria Raffaella Zocchi3 1Molecular Oncology and Angiogenesis Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy 2Immunology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy 3Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy It is well established that natural killer (NK) cells are involved in both innate and adaptive immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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