Integrin α7 correlates with worse clinical features and prognosis, and its knockdown inhibits cell proliferation and stemness in tongue squamous cell carcinoma.

In conclusion, ITGA7 knockdown inhibited tumor cell proliferation and stemness in TSCC cells. These findings indicated that ITGA7 might serve as a potential marker for CSCs and may correlate with worse clinical features and prognosis in TSCC. PMID: 31789398 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31789398?dopt=Abstract

Source: International Journal of Oncology - November 28, 2019 Category: Cancer & Oncology Authors: Lv Z, Yang Y, Yang C Tags: Int J Oncol Source Type: research