Reverse transcriptase multiplex ligation-dependent probe amplificatioN IN ENDOMYOCARDIAL BIOPSIES for the diagnosis of cardiac allograft rejection

Molecular biology has emerged as a potential companion to histology for the diagnosis of rejection after heart transplantation. Reverse transcriptase multiplex ligation-dependent probe amplification (RT-MLPA) is a technique of targeted gene expression analysis suitable for formalin-fixed paraffin-embedded (FFPE) biopsies. Our aim was to assess RT-MLPA for the diagnosis of allograft rejection in heart transplantation.

Source: The Journal of Heart and Lung Transplantation - November 25, 2019 Category: Transplant Surgery Authors: Nicolas Adam, Guillaume Coutance, Pierre-Julien Viailly, Fanny Drieux, Philippe Ruminy, Ahmad Abdel Sater, Claire Toquet, Philippe Rouvier, Arnaud Fran çois, Marie-Pierre Chenard, Eric Epailly, Romain Guillemain, Sabine Pattier, Arnaud Gay, Shaida Varnou Tags: Original Clinical Science Source Type: research