Evaluation of P16 as a surrogate marker for transcriptionally active HPV status of Oropharyngeal Squamous Cell Carcinoma in an eastern Chinese population

Conclusion: Solitary P16 IHC is insufficient for HPV status detection for OPSCC patients with tobacco and/or alcohol exposure but perform better for those without exposure, and additional HPV DNA specific testing may be necessary for accurate HPV status determination.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research