Differences between men and women with COPD: The French Palomb Cohort

This study aimed to compare the COPD severity (GOLD III-IV vs I-II) in both women and men in PALOMB cohort.Diagnosed COPD patients were included by their pulmonologists. The following variables were collected: age, sex, BMI, FEV1, dyspnea (mMRC), the frequency of exacerbations, static hyperinflation (RV/TLC ≥130%) and comorbidities.35.64% of 2,259 COPD patients followed were women (64 average age). Statistically significant (P≤0.001) findings in female COPD patients were as follows: younger, underweight, more likely to be current cigarette smokers, more frequent static hyperinflation (76.1% vs 70.6%) and higher dyspnea. GOLD stage III was lower in women. Exacerbator phenotype was more frequent in women (31.9% vs 23.2%), regardless of their COPD severity. Anxiety (22.7% vs 9.2%) and depression (23.7% vs 9.2%) were more frequent in women. Adjusted multivariate analysis showed that: Hyperinflation: 5.78[3.99-8.36]; higher dyspnea: 2.74[1.96-3.82]; anxiety: 2.04[1.47-2.84]; asthma: 1.55[1.05-2.3] and frequent exacerbations: 1.39[1.04-1.86] were associated with COPD severity in women. Contrastingly in men: Hyperinflation: 7.39[5.81-9.4]; higher dyspnea: 2.8[2.21-3.54]; left heart failure: 1.75[1.13-2.71]; sputum: 1.62[1.32-2]; age: 1.39[1.11-1.74] and hypertension: 1.27[1.03-1.58] were associated with COPD severity.The results are reflective of the commonly found factors of poor prognosis in COPD women: Frequent exacerbations and underweight.Funding: Bordeaux University Foun...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research

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CONCLUSION: Individuals with DD undergoing PMT presented higher rates of recurrence of periodontitis and tooth loss when compared to individuals without DD. Additionally, the interaction between DD and smoking significantly increased the risk for the recurrence of periodontitis. PMID: 32224545 [PubMed - in process]
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
Publication date: Available online 31 March 2020Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Joanna Owsianowska, Magdalena Sylwia Kamińska, Mateusz Bosiacki, Dariusz Chlubek, Beata Karakiewicz, Anna Jurczak, Marzanna Stanisławska, Katarzyna Barczak, Elżbieta Grochans
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
No abstract available
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: State of Public Health Source Type: research
ConclusionsWeight loss after EGJR is sustained up to 5  years after revision with little effect on medical comorbidities. Patients with a greater reduction in stoma diameter experienced superior weight loss.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Authors: Matsumura E, Nohara K, Tanaka N, Fujii N, Sakai T Abstract Polypharmacy in elderly persons living at home or in a nursing home is an issue. In the field of dentistry, strategies to reduce polypharmacy must be promoted; however, there is insufficient basic data on medications received by elderly persons with dysphagia living at home or in a nursing home. The subjects were 106 elderly persons with dysphagia living at home or in a nursing home. Based on their medical records, the presence of disease and number/type of drugs being administered were investigated. Stroke, dementia, and hypertension were common. ...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
TWiV covers trials of hydroxychloroquine and convalescent plasma therapy for COVID-19, and answers listener questions on blood tests for antibodies, cross-protection among coronaviruses, acquiring infection from food or the gas pump, face masks containing copper, and much more. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Emergency use of hydroxychloroquine (FDA) Trial of hydroxycholorquine in COVID-19 patients (China, France) COVID-19 in critically ill patients, Seattle (NE...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
In a blog post last week, I shared an excerpt from the new book that Paul Cerrato and I just completed,The Transformative Power of Mobile Medicine. Here is a second excerpt from Chapter 3,  “Exploring the Strengths and Weaknesses of Mobile Health Apps.”Even patients who are fully engaged in their own care still need access to medical apps they can trust. The IQVIA Institute for Human Data Science has performed a detailed analysis of the clinical evidence supporting mobile health apps, rating their maturity and relative quality. Its rating scale places a single observational study near the bottom of th...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
This study aimed to generate real-world evidence to assess the burden of comorbidities in COPD patients, to effectively manage these patients and optimize the associated healthcare resource allocation. ARCTIC is a large, real-world, retrospective cohort study conducted in Swedish COPD patients using electronic medical record data collected between 2000 and 2014. These patients were studied for prevalence of various comorbidities and for association of these comorbidities with exacerbations, mortality, and healthcare costs compared with an age-, sex-, and comorbidities-matched non-COPD reference population. A total of 17,47...
Source: Primary Care - Category: Primary Care Authors: Tags: NPJ Prim Care Respir Med Source Type: research
Conclusion: PM2.5 was associated with depressive and anxiety symptoms, with associations the strongest among individuals with lower SES or among those with certain health-related characteristics. Citation: Pun VC, Manjourides J, Suh H. 2017. Association of ambient air pollution with depressive and anxiety symptoms in older adults: results from the NSHAP study. Environ Health Perspect 125:342–348; http://dx.doi.org/10.1289/EHP494 Address correspondence to H. Suh, Department of Civil and Environmental Engineering, Tufts University, Medford, MA 02153 USA. Telephone: (617) 627-2941. Email: Helen.Suh@tufts.edu We ack...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Articles March 2017 Source Type: research
Conclusion: Comorbid disease was frequently recorded in this asthma population. All-cause mortality for the study population did not differ from the Swedish population overall, but a higher death rate due to pulmonary causes (mainly COPD) was seen among the asthma patients.Sponsor: AstraZeneca.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 1.6 General Practice and Primary Care Source Type: research
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