Combination Checkpoint Inhibitor Therapy Induces Multiple Immune Major Related Adverse Events in the Treatment of Vaginal Melanoma: A Cautionary Case Report

ConclusionICIs have demonstrated the ability to induce improved long-term survival in metastatic cutaneous or mucosal melanomas, including those of gynecologic origin. As ICI therapy becomes more widespread, healthcare providers across all fields of medicine need be vigilant to recognize the symptoms of irAEs that can often masquerade as common illnesses to prevent potentially dangerous irreversible immune toxicities.
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research